Below, we demonstrate that conolidine, a pure analgesic alkaloid used in classic Chinese medicine, targets ACKR3, thereby providing further proof of the correlation among ACKR3 and agony modulation and opening alternate therapeutic avenues for that treatment of Long-term agony. The 1st asymmetric complete synthesis of conolidine was developed by https://wardb025hzx5.ja-blog.com/profile